tert-Butyl is an organic compound with the chemical formula C12H23N2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: tert-Butyl is a colorless liquid.
-Melting point: approximately -10°C.
-Boiling point: approximately 250°C.
-Density: Approximately 0.977g/cm³.
-Solubility: Soluble in most organic solvents, such as ethanol, methanol and ether.
Use:
- tert-Butyl can be used as an intermediate in organic synthesis and for the synthesis of other organic compounds.
-In the field of drug research and development, it can also be used as a raw material to synthesize various drugs.
Method:
The synthesis of tert-Butyl can be carried out by the following steps:
1.4-amino -3-methyl -1-pipecolic acid is reacted with tert-butyl chloroformate under alkaline conditions.
2. carry out esterification reaction to react the carboxyl group in the reaction product with alcohol to generate tert-Butyl.
Safety Information:
- tert-Butyl is a flammable liquid and should be kept away from fire and high temperature.
-When using, pay attention to avoid contact with skin, eyes, etc., so as to avoid damage.
-When using or storing, follow proper laboratory safety procedures and wear appropriate protective equipment such as gloves, goggles and protective clothing.
-If inhaled or eaten, seek medical attention immediately.